How To Use Linzess For Weight Loss (With Possible Side Effects)

How To Use Linzess For Weight Loss (With Possible Side Effects)

Linzess is the brand name for the medication linaclotide. It’s a prescription drug used to treat persistent constipation and you can also use linzess for weight loss.

The primary function of linzess is to boost the release of two chemical substances termed chloride and bicarbonate in the intestines. It results in the formation of more intestinal fluid, which facilitates stool movement.

Additionally, Linzess works by speeding up the passage of food through the digestive system.

IBS-C and chronic idiopathic constipation are two forms of chronic constipation that can be treated with linzess. Constipation lasts for three months or more in either of these situations.

How to use linzess for weight loss

Although legally, you cannot use linzess for weight loss because it is not yet licensed to treat weight loss. However, some people who use linzess for weight loss have significantly dropped weight.

When taking Linzess for chronic constipation, some people may lose weight.

weight loss

It could result from the medication’s potential to cause diarrhea and the loss of electrolytes and water from the body, which, if left untreated, can result in weight loss.

When taking Linzess, diarrhea frequently starts within the first two weeks, and about 20% of IBS-C patients experience diarrhea.

Mild diarrhea is expected when taking Linzess, but if you experience severe diarrhea, you should cease taking the medication and consult your physician. It is crucial for elderly persons who may be more susceptible to dehydration.

How does linzess work for losing weight?

Linzess works by increasing the amount of fluid in your intestines and assisting with the digestion of food more quickly.

Furthermore, linaclotide may improve the consistency of the stools and minimize symptoms such as bloating, stomach pain or stiffness, straining, and the feeling that the bowel movements are incomplete.

Additionally, taking linaclotide with food may exacerbate gastrointestinal side effects such as diarrhea. Linaclotide should be taken on an empty stomach at least 30 minutes before the first meal to reduce the risk of gastrointestinal intolerance.

This medication should be taken orally on an empty stomach at least 30 minutes before your first meal. Capsules are taken at once not to be chewed or broken.

If you have difficulty taking it, you can open the tablet and dissolve the contents with a teaspoon of applesauce. Right quickly, without chewing, swallow the mixture.

Side effects of using linzess for weight loss

side effects of using linzess for weight loss
side effects of using linzess for weight loss

When using linzess for weight loss, the side effects can range from minor to severe. They could change depending on the ailment the medication is used to treat. The following are Linzess’ most common side effects:

  • Diarrhea
  • Flatulence
  • Headache
  • Inflammation of the intestine
  • Abdominal pain
  • Abdominal distension

The most frequent adverse effect of Linzess is diarrhea since it reduces gastrointestinal transit time. While it may be distressing to experience one or more of these adverse effects while taking Linzess, many people will start to find relief from their persistent constipation soon after starting the medication.

Severe side effects of Linzess

Linzess occasionally produces more severe side effects that may require medical treatment. They consist of the following:

Severe diarrhea

You should stop using Linzess and consult your doctor to determine whether continuing the medication is good for you if you experience diarrhea while taking the drug that worsens or won’t go away, particularly if you have bloody or black stools.

Medical guidance on what to do is made available from your doctor. Rarely, severe diarrhea can cause fainting or disorientation, necessitating hospitalization to replenish electrolytes lost to dehydration.


An extreme allergic reaction to a substance, food, or venom is known as anaphylaxis. It is highly uncommon for someone to experience an allergic response to Linzess. Still, it is feasible, and untreated anaphylaxis can be highly harmful.

You should get medical help immediately if you begin to have breathing problems, throat swelling, nausea, vomiting, shock, and hives after taking Linzess.


There isn’t much evidence that Linzess contributes to depression. Still, there might be a connection between depression, anxiety, and IBS-C. It is due to the nervous system’s role in the gut’s partial control over the brain’s ability to process information.

IBS-C patients are thought to experience anxiety and depressive symptoms in roughly 50% of cases. Suppose someone taking Linzess for IBS-C feels worried or sad. In that case, it may not be because of the medicine but rather their anxiety or depression.

Allergic reaction

As with most medications, taking Linzess can cause an adverse reaction in some people. A mild allergic reaction may result in skin rashes, itching, or flushing. Although uncommon, an allergic reaction with greater severity is likely to occur.

Swelling under your skin, usually in your eyelids, lips, hands, or feet; swelling of your tongue, mouth, or throat; and breathing difficulties are just a few signs of a severe allergic reaction.

How long are the adverse effects of Linzess?

Diarrhea is the most frequent adverse reaction for most Linzess users, and it typically starts within the first two weeks of medication. In clinical trials, roughly 33% of patients had their diarrhea go away in a week. Although many side effects go away quickly, it’s possible to experience side effects that last a while.

It varies from person to person and how their body processes Linzess because some people get diarrhea that lasts up to a month.

It may be a good idea to speak with your doctor to be sure that what you’re experiencing is normal if you’ve been taking Linzess for longer than two weeks and your side effects aren’t fading.

Linzess does not act instantly and is not a laxative. About a week after taking Linzess, most people have relief from their symptoms of chronic constipation, and IBS-C patients often experience improvements in their health for 12 weeks.


Is Linzess safe to use when pregnant?

Linzess has a localized effect on the intestinal lumen and is converted internally into peptides without entering the bloodstream.
Despite not being incorporated into the systemic circulation, its usage may be linked to electrolyte imbalance and dehydration. The fetus can suffer from electrolyte imbalance and dehydration. As a result, it is advised against using it during pregnancy.

Can you use linzess for weight loss or gain?

No, Linzess doesn’t make you gain or lose weight. However, it can result in diarrhea, which in some circumstances may induce weight loss. Linzess, on the other hand, can result in bloating, which might result in weight gain.

Can you use linzess for weight loss or gain?

No, Linzess doesn’t make you gain or lose weight. However, it can result in diarrhea, which in some circumstances may induce weight loss. Linzess, on the other hand, can result in bloating, which might result in weight gain.
Some patients with IBS-C (irritable bowel syndrome with constipation) may gain or lose weight due to their condition. For instance, some IBS-C patients may struggle to absorb particular foods or metabolize minerals. Weight loss could result from this.

How long does linzess take to work?

When you take your first dose of Linzess, it should start working immediately. Before your constipation symptoms start to improve, it can take up to a week. But it can take some time before you start to feel your symptoms subside. Over the following 12 weeks, the medication may continue to function even more effectively.
The half-life of Linzess is unknown because the body absorbs it poorly. The time it takes for the body to remove half of a dose of medicine is known as the half-life. Linzess operates in your digestive system as opposed to being absorbed into your blood.


For some types of constipation, doctors may recommend the drug Linzess. Especially IBS-related constipation. You only need to take it once daily, which is available in capsule form.

Linzess can result in adverse effects for some people, much like other prescription drugs. Loss of appetite is one of the adverse effects. Some people desire to utilize capsules as a weight loss supplement because the connection between the pills and appetite has become widely recognized.

Although individuals may use linzess for weight loss, it can also increase weight in others. The reason for this is uncertain. Linzess is not intended to serve as a tool for weight loss; hence the issue has not been appropriately evaluated.

We specifically recommend you this article: How To Use An Acupressure Mat For Weight Loss

About The Author

Scroll to Top
Scroll to Top